ZFP57

Also known as C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2, ZFP57 zinc finger protein

Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene.

In the Vinony graph

Within Vinony's link graph, ZFP57 is referenced by 84 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 6.

Its subject is documented across 6 Wikipedia language editions.

Gene data

ZFP57

Name: ZFP57 zinc finger protein
Type: protein-coding
Position: 29,672,482–29,681,174 (−)
Aliases: C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2
Ensembl: ENSG00000234669
RefSeq RNA: NM_001109809.5, NM_001366333.2
RefSeq protein: NP_001103279.2, NP_001353262.1

The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).[provided by RefSeq, Sep 2009].

Gene Ontology

Biological process

regulation of DNA-templated transcription regulation of transcription by RNA polymerase II autosome genomic imprinting

Molecular function

RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific chromatin binding protein binding

Cellular component

nucleus nucleus nucleus

Pathways

Herpes simplex virus 1 infection - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

ZFP57 zinc finger protein

Symbol: ZFP57
Biotype: Protein coding
Organism: Homo sapiens
Location: Chr HSCHR6_MHC_COX_CTG1:1,158,865-1,167,618
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 9 more facts

HomoloGene ID: 7603
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/346171
chromosome: human chromosome 6
genomic start: 29672483
genomic end: 29681155
cytogenetic location: 6p22.1
genetic association: transient neonatal diabetes mellitus
expressed in: caudate nucleus

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections

Contents

Function
Clinical significance
References
Further reading

Zinc finger protein 57 homolog (ZFP57), also known as zinc finger protein 698 (ZNF698), is a protein that in humans is encoded by the ZFP57 gene.

== Function == The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor.

Excerpted from Wikipedia’s “ZFP57” article, available under the CC BY-SA 4.0 licence.