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زیپپرول

Structure via PubChem · Public domain (PubChem)

EntityQ4024559· pop 9· linked from 247 articles

زیپپرول

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Zipeprol is a centrally acting cough suppressant developed in France in the 1970s. It is not a morphinan derivative (in contrast to both codeine and dextromethorphan). Zipeprol acts as a local anaesthetic and has mucolytic, antihistamine and anticholinergic properties. It is sold with several brand names such as Zinolta and Respilene. It is not available in the United States or Canada and has been discontinued in Europe. It is still available in some countries in Asia and South America.

Chemical data

Formula
C23H32N2O3
Molecular weight
384.5 g/mol
IUPAC name
1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-2-ol
SMILES
COC(CN1CCN(CC1)CC(C(C2=CC=CC=C2)OC)O)C3=CC=CC=C3
InChIKey
VSTNNAYSCJQCQI-UHFFFAOYSA-N
XLogP
2.2
Polar surface area
45.2 Ų
H-bond donors
1
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Withdrawn
Max clinical phase
Approved
Molecule type
Small molecule
Indications
Cough

via ChEMBL · EBI

Wikidata facts

Mass
384.241
Show 3 more facts
chemical formula
C₂₃H₃₂N₂O₃
canonical SMILES
COC(CN1CCN(CC1)CC(C(C2=CC=CC=C2)OC)O)C3=CC=CC=C3
subject has role
antitussive
Sources (2)

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