5-HTP
Also known as 5-hydroxytryptophan, 5-hydroxy-tryptophan, Oxitriptan, 5-Hydroxytryptophan L-form, 5-Hydroxy-L-Tryptophan, Hydroxy-5 L-tryptophane, L-5-Hydroxytryptophan, Tript-OH
5-Hydroxytryptophan (5-HTP), used medically as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
Chemical data
- Formula
- C11H12N2O3
- Molecular weight
- 220.22 g/mol
- IUPAC name
- (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
- SMILES
- C1=CC2=C(C=C1O)C(=CN2)C[C@@H](C(=O)O)N
- InChIKey
- LDCYZAJDBXYCGN-VIFPVBQESA-N
- XLogP
- -1.2
- Polar surface area
- 99.3 Ų
- H-bond donors
- 4
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
~7 min read
Article
8 sectionsContents
- Production
- Metabolism
- Dietary sources
- Use as a medication and supplement
- Research
- Psychedelic effects
- See also
- References
5-Hydroxytryptophan (5-HTP), used medically as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin.
5-HTP can be manufactured and used as a drug and supplement with the oxitriptan. Brand names include Cincofarm, Levothym, Levotonine, Oxyfan, Telesol, Tript-OH, and Triptum. As a drug, it is used in the treatment of depression and for certain other indications.