Structure via PubChem · Public domain (PubChem)
6-hydroxyflavone
Sign in to saveAlso known as 6-Hydroxy-2-phenyl-4-benzopyrone
6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in Crocus and leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydroxyflavone shows anxiolytic activity in a mouse model. Compared to the full agonist diazepam, 6-hydroxyflavone was approximately 200 times less potent.
In the Vinony graph
Within Vinony's link graph, 6-hydroxyflavone is referenced by 65 other articles, and connects out to International Standard Book Number, digital object identifier and chemical formula.
It sits within the topics Chembox image size set, Chemical articles with multiple compound IDs and ECHA InfoCard ID from Wikidata.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C15H10O3
- Molecular weight
- 238.24 g/mol
- IUPAC name
- 6-hydroxy-2-phenylchromen-4-one
- SMILES
- C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O
- InChIKey
- GPZYYYGYCRFPBU-UHFFFAOYSA-N
- XLogP
- 3.6
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- flavone
- Mass
- 238.063
Show 5 more facts
- chemical formula
- C₁₅H₁₀O₃
- canonical SMILES
- C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O
- melting point
- 235.0
- found in taxon
- Scutellaria baicalensis
- Commons category
- 6-Hydroxyflavone
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in Crocus and leaves of Barleria prionitis Linn. (a common Acanthaceae from India). 6-Hydroxyflavone shows anxiolytic activity in a mouse model. Compared to the full agonist diazepam, 6-hydroxyflavone was approximately 200 times less potent.
== References ==
Excerpted from Wikipedia’s “6-hydroxyflavone” article, available under the CC BY-SA 4.0 licence.