ABRAXAS2

Also known as ABRO1, KIAA0157, FAM175B, family with sequence similarity 175 member B, abraxas 2, BRISC complex subunit

BRISC complex subunit Abro1 is a protein that in humans is encoded by the FAM175B gene.

Gene data

ABRAXAS2

Name: abraxas 2, BRISC complex subunit
Type: protein-coding
Position: 124,801,805–124,836,670 (+)
Aliases: ABRO1, FAM175B, KIAA0157
Ensembl: ENSG00000165660
RefSeq RNA: NM_032182.4, XM_047424888.1, XM_047424889.1, XM_047424891.1, XM_054365317.1
RefSeq protein: NP_115558.3, XP_047280844.1, XP_047280845.1, XP_047280847.1, XP_054221292.1

Enables microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Involved in several processes, including mitotic spindle assembly; protein K63-linked deubiquitination; and response to ischemia. Located in cytoplasm. Part of BRISC complex. Colocalizes with microtubule minus-end; midbody; and spindle pole centrosome. [provided by Alliance of Genome Resources, Apr 2022]