IST1
Sign in to saveAlso known as OLC1, KIAA0174, IST1, ESCRT-III associated factor, CHMP8, IST1 factor associated with ESCRT-III
IST1 homolog is a protein that in humans is encoded by the KIAA0174 gene.
Gene data
IST1- Name
- IST1 factor associated with ESCRT-III
- Type
- protein-coding
- Position
- 71,845,970–71,931,199 (+)
- Aliases
- CHMP8, OLC1
- Ensembl
- ENSG00000182149
- RefSeq RNA
- NM_001270975.2, NM_001270976.1, NM_001270977.2, NM_001270978.2, NM_001270979.1
- RefSeq protein
- NP_001257904.1, NP_001257905.1, NP_001257906.1, NP_001257907.1, NP_001257908.1
This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
IST1 factor associated with ESCRT-III
- Symbol
- IST1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:71,845,970-71,931,199
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein KIAA0174 PDB 3FRR.png
Show 8 more facts
- HomoloGene ID
- 8849
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9798
- genomic end
- 71962913
- genomic start
- 71879899
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.2
- expressed in
- anterior pituitary
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
IST1 homolog is a protein that in humans is encoded by the KIAA0174 gene.
==References==
Excerpted from Wikipedia’s “IST1” article, available under the CC BY-SA 4.0 licence.