acetonylacetone

Also known as CH3COCH2CH2COCH3, NSC 7621, alpha,beta-diacetylethane, Acetonyl acetone, 2,5-Diketohexane, 1,2-Diacetylethane, 2,5-Hexadione, hexane-2,5-dione

2,5-Hexanedione (Acetonylacetone) is an aliphatic diketone. It is a colorless liquid. In humans, it is a toxic metabolite of hexane and of 2-hexanone.

Research

657 papers

2,5-hexanedione-induced testicular injury.Annual review of pharmacology and toxicology · 2003
Dimercaptols of acetonylacetone.Journal of the American Chemical Society · 1948
The noncoincidence phenomenon of acetonylacetone C[double bond, length as m-dash]O stretching in a binary mixture and the aggregation-induced split theory.RSC advances · 2020
Detection and disaggregation of amyloid fibrils by luminescent amphiphilic platinum(II) complexes.Dalton transactions (Cambridge, England : 2003) · 2024
Real-time monitoring of the reaction between aniline and acetonylacetone using extractive electorspray ionization tandem mass spectrometry.Scientific reports · 2019

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Article

5 sections

Contents

Symptoms of poisoning
Mechanism of action
Synthesis
Uses
References

2,5-Hexanedione (Acetonylacetone) is an aliphatic diketone. It is a colorless liquid. In humans, it is a toxic metabolite of hexane and of 2-hexanone.

==Symptoms of poisoning== The chronic toxicity of hexane is attributed to hexane-2,5-dione. The symptoms are tingling and cramps in the arms and legs, followed by general muscular weakness. In severe cases, atrophy of the skeletal muscles is observed, along with a loss of coordination and vision problems.