Gene data
ACTB- Name
- actin beta
- Type
- protein-coding
- Position
- 5,526,409–5,563,902 (−)
- Aliases
- BKRNS, BNS, BRWS1, CSMH, DDS1, PS1TP5BP1, THC8
- Ensembl
- ENSG00000075624
- RefSeq RNA
- NM_001101.5
- RefSeq protein
- NP_001092.1
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017].
Gene Ontology
Biological process
Molecular function
Pathways
Rap1 signaling pathway - Homo sapiens (human)Phagosome - Homo sapiens (human)Apoptosis - Homo sapiens (human)Hippo signaling pathway - Homo sapiens (human)Focal adhesion - Homo sapiens (human)Adherens junction - Homo sapiens (human)Tight junction - Homo sapiens (human)Platelet activation - Homo sapiens (human)Neutrophil extracellular trap formation - Homo sapiens (human)Leukocyte transendothelial migration - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
actin beta
- Symbol
- ACTB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:5,526,409-5,563,902
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ACTB PDB 1atn.png
Show 8 more facts
- HomoloGene ID
- 110648
- chromosome
- human chromosome 7
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/60
- genomic start
- 5526409
- genomic end
- 5563902
- cytogenetic location
- 7p22.1
- expressed in
- olfactory bulb
via Wikidata · CC0