ADGRL3
Sign in to saveAlso known as CIRL3, LEC3, CL3, LPHN3, adhesion G protein-coupled receptor L3
protein-coding gene in the species Homo sapiens
Gene data
ADGRL3- Name
- adhesion G protein-coupled receptor L3
- Type
- protein-coding
- Position
- 61,200,112–62,078,335 (+)
- Aliases
- CIRL3, CL3, LEC3, LPHN3
- Ensembl
- ENSG00000150471
- RefSeq RNA
- NM_001322246.3, NM_001322402.3, NM_001371342.1, NM_001371343.2, NM_001371344.2
- RefSeq protein
- NP_001309175.1, NP_001309331.1, NP_001358271.1, NP_001358272.1, NP_001358273.1
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor L3
- Symbol
- ADGRL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:61,200,112-62,078,335
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI