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GeneQ18037062· pop 5· linked from 486 articles

Also known as CIRL3, LEC3, CL3, LPHN3, adhesion G protein-coupled receptor L3

protein-coding gene in the species Homo sapiens

Gene data

ADGRL3
Name
adhesion G protein-coupled receptor L3
Type
protein-coding
Position
61,200,112–62,078,335 (+)
Aliases
CIRL3, CL3, LEC3, LPHN3
RefSeq RNA
NM_001322246.3, NM_001322402.3, NM_001371342.1, NM_001371343.2, NM_001371344.2
RefSeq protein
NP_001309175.1, NP_001309331.1, NP_001358271.1, NP_001358272.1, NP_001358273.1

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

adhesion G protein-coupled receptor L3

Symbol
ADGRL3
Biotype
Protein coding
Organism
Homo sapiens
Location
4:61,200,112-62,078,335
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

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