ANAPC10
Sign in to saveAlso known as APC10, DOC1, anaphase promoting complex subunit 10
Anaphase-promoting complex subunit 10 is an enzyme that in humans is encoded by the ANAPC10 gene.
In the Vinony graph
Within Vinony's link graph, ANAPC10 is referenced by 3 other articles, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 4 Wikipedia language editions.
Gene data
ANAPC10- Name
- anaphase promoting complex subunit 10
- Type
- protein-coding
- Aliases
- APC10, DOC1
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011].
via MyGene.info
Gene · Ensembl
anaphase promoting complex subunit 10
- Symbol
- ANAPC10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:144,831,908-145,098,823
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein ANAPC10 PDB 1jhj.png
Show 8 more facts
- HomoloGene ID
- 32238
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10393
- genomic end
- 146019693
- genomic start
- 144831908
- chromosome
- human chromosome 4
- cytogenetic location
- 4q31.21
- expressed in
- gastrocnemius muscle
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
Anaphase-promoting complex subunit 10 is an enzyme that in humans is encoded by the ANAPC10 gene.
== Interactions ==
Excerpted from Wikipedia’s “ANAPC10” article, available under the CC BY-SA 4.0 licence.