APOM

Also known as G3a, HSPC336, NG20, apo-M, apolipoprotein M

Apolipoprotein M is an apolipoprotein and member of the lipocalin protein family that in humans is encoded by the APOM gene. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully characterized. It lacks an external amphipathic motif and is uniquely secreted t

Gene data

APOM

Name: apolipoprotein M
Type: protein-coding
Chromosome: HSCHR6_MHC_MANN_CTG1
Position: 2,957,462–2,963,256 (+)
Aliases: G3a, HSPC336, NG20, apo-M
Ensembl: ENSG00000235754
RefSeq RNA: NM_001256169.2, NM_019101.3, NR_045828.2, XM_006715150.4, XM_054329835.1
RefSeq protein: NP_001243098.1, NP_061974.2, XP_006715213.1, XP_054185810.1, XP_054186294.1

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012].