PLA2G2A
Sign in to saveAlso known as MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2, phospholipase A2 group IIA
Phospholipase A2, membrane associated is an enzyme that in humans is encoded by the PLA2G2A gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to PLA2G2A, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 6 Wikipedia language editions.
Gene data
PLA2G2A- Name
- phospholipase A2 group IIA
- Type
- protein-coding
- Position
- 19,975,431–19,980,462 (−)
- Aliases
- MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
- Ensembl
- ENSG00000188257
- RefSeq RNA
- NM_000300.4, NM_001161727.2, NM_001161728.2, NM_001161729.1, NM_001395463.1
- RefSeq protein
- NP_000291.1, NP_001155199.1, NP_001155200.1, NP_001155201.1, NP_001382392.1
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phospholipase A2 group IIA
- Symbol
- PLA2G2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:19,975,431-19,980,462
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PLA2G2A PDB 1ayp.png
Show 8 more facts
- HomoloGene ID
- 254
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5320
- genomic end
- 20306932
- genomic start
- 20301925
- chromosome
- human chromosome 1
- cytogenetic location
- 1p36.13
- expressed in
- rectum
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Phospholipase A2, membrane associated is an enzyme that in humans is encoded by the PLA2G2A gene.
==See also== Phospholipase A2
Excerpted from Wikipedia’s “PLA2G2A” article, available under the CC BY-SA 4.0 licence.