PLSCR2
Sign in to saveAlso known as phospholipid scramblase 2
Phospholipid scramblase 2, also known as Ca2+-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.
Gene data
PLSCR2- Name
- phospholipid scramblase 2
- Type
- protein-coding
- Position
- 146,391,421–146,495,991 (−)
- Ensembl
- ENSG00000163746
- RefSeq RNA
- NM_001199978.3, NM_001199979.1, NM_001395437.1, NM_001395438.1, NM_001395439.1
- RefSeq protein
- NP_001186907.1, NP_001186908.1, NP_001382366.1, NP_001382367.1, NP_001382368.1
This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
phospholipid scramblase 2
- Symbol
- PLSCR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:146,391,366-146,495,991
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 124471
- exact match
- identifiers.org/ncbigene/57047
- genomic end
- 146213778
- genomic start
- 146109208
- cytogenetic location
- 3q24
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- See also
- References
- Further reading
Phospholipid scramblase 2, also known as Ca2+-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.
== See also == scramblase