DUSP22
Sign in to saveAlso known as JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX
Dual specificity protein phosphatase 22 is an enzyme that in humans is encoded by the DUSP22 gene.
Gene data
DUSP22- Name
- dual specificity phosphatase 22
- Type
- protein-coding
- Position
- 291,630–351,355 (+)
- Aliases
- JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX
- Ensembl
- ENSG00000112679
- RefSeq RNA
- NM_001286555.3, NM_020185.6, NR_104473.3, NR_104474.3, NR_104475.3
- RefSeq protein
- NP_001273484.1, NP_064570.1, XP_011513059.1, XP_016866551.1, XP_054211915.1
Enables non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in plasma membrane. Part of cytoplasm; filamentous actin; and leading edge of lamellipodium. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
dual specificity phosphatase 22
- Symbol
- DUSP22
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:291,630-369,379
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- PBB Protein DUSP22 image.jpg
Show 5 more facts
- HomoloGene ID
- 86039
- exact match
- identifiers.org/ncbigene/56940
- genomic end
- 351355
- genomic start
- 291630
- cytogenetic location
- 6p25.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Dual specificity protein phosphatase 22 is an enzyme that in humans is encoded by the DUSP22 gene.
==References==