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AR-R17779

Structure via PubChem · Public domain (PubChem)

EntityQ4653530· pop 5· linked from 779 articles

AR-R17779 is a drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine receptors. It has nootropic effects in animal studies, but its effects do not substitute for those of nicotine. It has also been studied as a potential novel treatment for arthritis.

Chemical data

Formula
C9H14N2O2
Molecular weight
182.22 g/mol
IUPAC name
(5S)-spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one
SMILES
C1CN2CCC1[C@@]3(C2)CNC(=O)O3
InChIKey
TYAGAVRSOFABFO-VIFPVBQESA-N
XLogP
0.2
Polar surface area
41.6 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
182.105528
Show 5 more facts
chemical formula
C₉H₁₄N₂O₂
canonical SMILES
C1CN2CCC1C3(C2)CNC(=O)O3
isomeric SMILES
C1CN2CCC1[C@@]3(C2)CNC(=O)O3
Commons category
AR-R17779
subject has role
nootropic
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

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Contents
  • References

AR-R17779 is a drug that acts as a potent and selective full agonist for the α7 subtype of neural nicotinic acetylcholine receptors. It has nootropic effects in animal studies, but its effects do not substitute for those of nicotine. It has also been studied as a potential novel treatment for arthritis.

== References==

Excerpted from Wikipedia’s “AR-R17779” article, available under the CC BY-SA 4.0 licence.

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