Structure via PubChem · Public domain (PubChem)
azilsartan
Sign in to saveAlso known as TAK 536, TAK-536, TAK536
Azilsartan, sold under the brand name Edarbi among others, is used for the treatment of hypertension. It is used as the prodrug azilsartan medoxomil, is an angiotensin II receptor antagonist, and was developed by Takeda.
In the Vinony graph
Within Vinony's link graph, azilsartan is referenced by 87 other articles, and connects out to angiotensins, amlodipine/valsartan and biological half-life.
It sits within the topics Angiotensin II receptor antagonists, Benzimidazoles and Biphenyls.
Its subject is documented across 20 Wikipedia language editions.
Key facts
- Drug.legal_status
- Rx-only
- Drug.bioavailability
- 60%
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 456077928
- Drug.image
- Azilsartan.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Edarbi, Azilva
- Drug.MedlinePlus
- a611028
- Drug.DailyMedID
- Azilsartan
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- C09
- Drug.ATC_suffix
- CA09
- Drug.legal_CA
- Rx-only
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.legal_EU
- Rx-only
- Drug.metabolism
- CYP2C9
via Wikipedia infobox
Chemical data
- Formula
- C25H20N4O5
- Molecular weight
- 456.4 g/mol
- IUPAC name
- 2-ethoxy-3-[[4-[2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
- SMILES
- CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)O
- InChIKey
- KGSXMPPBFPAXLY-UHFFFAOYSA-N
- XLogP
- 4.4
- Polar surface area
- 115 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 456.143
Show 4 more facts
- canonical SMILES
- CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)O
- World Health Organisation international non-proprietary name
- azilsartan
- chemical formula
- C₂₅H₂₀N₄O₅
- Commons category
- Azilsartan
via Wikidata · CC0
~6 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Contraindications
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Chemistry
- History
- References
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 456077928 | image = Azilsartan.svg | image_class = skin-invert-image | width = | alt = | caption = | USAN =
| pronounce = | tradename = Edarbi, Azilva | Drugs.com = | MedlinePlus = a611028 | DailyMedID = Azilsartan | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = C09 | ATC_suffix = CA09 | ATC_supplemental =
Excerpted from Wikipedia’s “azilsartan” article, available under the CC BY-SA 4.0 licence.