Structure via PubChem · Public domain (PubChem)
eprosartan
Sign in to saveAlso known as Eprozar®, SK-108566, Teveten®, (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid, (E)-2-butyl-1-(p-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid, (E)-alpha{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid, (e)-3-[2-N-Butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid, (e)-Alpha{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid
Eprosartan, sold under the brand name Teveten among others, is an angiotensin II receptor antagonist used for the treatment of high blood pressure.
Chemical data
- Formula
- C23H24N2O4S
- Molecular weight
- 424.5 g/mol
- IUPAC name
- 4-[[2-butyl-5-[(E)-2-carboxy-3-thiophen-2-ylprop-1-enyl]imidazol-1-yl]methyl]benzoic acid
- SMILES
- CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\CC3=CC=CS3)/C(=O)O
- InChIKey
- OROAFUQRIXKEMV-LDADJPATSA-N
- XLogP
- 4.5
- Polar surface area
- 121 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
439 papers- Eprosartan.2006
- Eprosartan.Drugs · 1998
- Eprosartan.2012
- The role of eprosartan in the management of essential hypertension: literature review and expert opinion.Expert review of cardiovascular therapy · 2024
- Eprosartan: a review of its use in the management of hypertension.Drugs · 2000
via PubMed
~2 min read
Encyclopedic overview
2 sectionsContents
- History
- References
{{Drugbox | Watchedfields = changed | verifiedrevid = 461094389 | image = Eprosartan.svg | image_class = skin-invert-image
| tradename = Teveten | Drugs.com = | MedlinePlus = a601237 | DailyMedID = Eprosartan | pregnancy_AU = D | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = By mouth | ATC_prefix = C09 | ATC_suffix = CA02
Excerpted from Wikipedia’s “eprosartan” article, available under the CC BY-SA 4.0 licence.