Bcl-xL
Sign in to savethumb|X-ray crystal structure of Bcl-xL with 1.76 Å resolution
In the Vinony graph
Within Vinony's link graph, Bcl-xL is referenced by 73 other articles, and connects out to signal transduction, mitochondrion and digital object identifier.
It sits within the topics Apoptosis and Mitochondria.
Its subject is documented across 5 Wikipedia language editions.
~3 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- Related proteins
- References
thumb|X-ray crystal structure of Bcl-xL with 1.76 Å resolution
B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria. It is a member of the Bcl-2 family of proteins, and acts as an anti-apoptotic protein by preventing the release of mitochondrial contents such as cytochrome c, which leads to caspase activation and ultimately, programmed cell death.
Excerpted from Wikipedia’s “Bcl-xL” article, available under the CC BY-SA 4.0 licence.