Also known as 2700049M22Rik, AI875481, AU022477, FP497, BH3 interacting domain death agonist
protein-coding gene in the species Homo sapiens
Gene data
BID- Name
- BH3 interacting domain death agonist
- Type
- protein-coding
- Aliases
- FP497
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020].
via MyGene.info
Gene · Ensembl
BH3 interacting domain death agonist
- Symbol
- BID
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:17,734,138-17,774,770
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- BID protein 2bid.png
Show 5 more facts
- HomoloGene ID
- 923
- exact match
- identifiers.org/ncbigene/637
- genomic end
- 18257536
- genomic start
- 18216906
- cytogenetic location
- 22q11.21
Sources (4)
via Wikidata · CC0
Connections
bcl-2 family
Entity
mitochondrion
Entity
Q180686
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apoptotic process
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signal transduction
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cytochrome c, somatic
Protein
caspase
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Ensembl genome database project
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protein
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International Standard Book Number
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Wikidata
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