BAK1

Name

BCL2 antagonist/killer 1

Type

protein-coding

Position

33,572,547–33,580,305 (−)

Aliases

BAK, BAK-LIKE, BCL2L7, CDN1

Ensembl

ENSG00000030110

RefSeq RNA

NM_001188.4, XM_011514779.4, XM_011514780.2, XM_047419194.1, XM_047419196.1

RefSeq protein

NP_001179.1, XP_011513081.1, XP_011513082.1, XP_047275150.1, XP_047275152.1

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

BCL2 antagonist/killer 1

Symbol

BAK1

Biotype

Protein coding

Organism

Homo sapiens

Location

6:33,568,791-33,580,305

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein BAK1 PDB 2ims.png

via Wikidata · CC0