befunolol
Sign in to saveAlso known as (RS)-1-{7-[2-hydroxy-3-(propan-2-ylamino)propoxy]- 1-benzofuran-2-yl}ethanone
Befunolol (INN) is a beta blocker with intrinsic sympathomimetic activity used in the management of open-angle glaucoma. It also acts as a β adrenoreceptor partial agonist. Befunolol was introduced in Japan in 1983 by Kakenyaku Kako Co. under the trade name Bentos.
Research
126 papers- Purification and characterization of befunolol reductase from rabbit liver.Chemical & pharmaceutical bulletin · 1989
- Long-term effects of befunolol on the corneal endothelium and the consensual ophthalmotonic reaction.Clinical therapeutics · 1992
- A beta-adrenergic partial agonist (befunolol) discriminates two different affinity sites.Japanese journal of pharmacology · 1986
- A derivative of befunolol, BFE-55, interacts with only the high affinity sites in beta-adrenoceptors.Canadian journal of physiology and pharmacology · 1987
- A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs.General pharmacology · 1985
via PubMed
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Encyclopedic overview
2 sectionsContents
- Synthesis
- References
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Excerpted from Wikipedia’s “befunolol” article, available under the CC BY-SA 4.0 licence.