biotransformation
Sign in to saveAlso known as biological transformation
Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. Increasingly, biotransformations are effected with purified enzymes. Major industries and life-saving technologies depend on biotransformations.
Research
9,216,952 papers- Biotransformation of halogenated compounds.Critical reviews in biotechnology · 1991
- Biotransformation of terpenes.Biotechnology advances · 2006
- Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota.Biotechnology advances · 2020
- Detoxification pathways in the liver.Journal of inherited metabolic disease · 1991
- Biocatalysis and biotransformation in Brazil: An overview.Biotechnology advances · 2015
via PubMed
~3 min read
Article
10 sectionsContents
- Advantages and disadvantages
- Historical
- Modern examples
- Pharmaceuticals
- Sugars
- Amino acids
- Acrylamide
- Biofuels
- See also
- References
Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. Increasingly, biotransformations are effected with purified enzymes. Major industries and life-saving technologies depend on biotransformations.
==Advantages and disadvantages== Compared to the conventional production of chemicals, biotransformations are often attractive because their selectivities can be high, limiting the coproduction of undesirable coproducts. Generally operating under mild temperatures and pressures in aqueous solutions, many biotransformations are "green". The catalysts, i.e. the enzymes, are amenable to improvement by genetic manipulation.