brimonidine
Also known as Alphagan®, Mirvaso®, UK14,304, UK14304, Bromoxidine, 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline, Brimonidinum
Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate.
Key facts
- Drug.legal_US
- Rx-only
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 459982442
- Drug.image
- Brimonidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 195
- Drug.tradename
- Alphagan, Mirvaso, Lumify, others
- Drug.MedlinePlus
- a601232
- Drug.DailyMedID
- Brimonidine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- Topical
- Drug.ATC_prefix
- D11
- Drug.ATC_suffix
Article
6 sectionsContents
- Medical uses
- Mechanism of action
- Society and culture
- Names
- References
- Further reading
Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate.
Common side effects when used in the eyes include itchiness, redness, and a dry mouth. Common side effects when used on the skin include redness, burning, and headaches. More significant side effects may include allergic reactions and low blood pressure. Use in pregnancy appears to be safe. When applied to the eye it works by decreasing the amount of aqueous humor made while increasing the amount that drains from the eye. When applied to the skin it works by causing blood vessels to contract.