Structure via PubChem · Public domain (PubChem)
brimonidine
Sign in to saveAlso known as Alphagan®, Mirvaso®, UK14,304, UK14304, Bromoxidine, 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline, Brimonidinum
Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate.
Key facts
- Drug.legal_US
- Rx-only
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 459982442
- Drug.image
- Brimonidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 195
- Drug.tradename
- Alphagan, Mirvaso, Lumify, others
- Drug.MedlinePlus
- a601232
- Drug.DailyMedID
- Brimonidine
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- Topical
- Drug.ATC_prefix
- D11
- Drug.ATC_suffix
- AX21
- Drug.ATC_supplemental
- , ,
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- /Schedule 2
- Drug.legal_US_comment
- / OTC
- Drug.metabolism
- Primarily liver
via Wikipedia infobox
Chemical data
- Formula
- C11H10BrN5
- Molecular weight
- 292.13 g/mol
- IUPAC name
- 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
- SMILES
- C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
- InChIKey
- XYLJNLCSTIOKRM-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 62.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 291.012
Show 4 more facts
- chemical formula
- C₁₁H₁₀BrN₅
- World Health Organisation international non-proprietary name
- brimonidine
- canonical SMILES
- C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
- Commons category
- Brimonidine
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Medical uses
- Mechanism of action
- Society and culture
- Names
- References
- Further reading
Brimonidine is an α2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin. It is also available in the fixed-dose combination medication brimonidine/timolol along with timolol maleate.
Common side effects when used in the eyes include itchiness, redness, and a dry mouth. Common side effects when used on the skin include redness, burning, and headaches. More significant side effects may include allergic reactions and low blood pressure. Use in pregnancy appears to be safe. When applied to the eye it works by decreasing the amount of aqueous humor made while increasing the amount that drains from the eye. When applied to the skin it works by causing blood vessels to contract.