BRMS1

Also known as breast cancer metastasis suppressor 1, BRMS1, transcriptional repressor and anoikis regulator, BRMS1 transcriptional repressor and anoikis regulator

Breast cancer metastasis suppressor 1 is a protein that in humans is encoded by the BRMS1 gene.

Gene data

BRMS1

Name: BRMS1 transcriptional repressor and anoikis regulator
Type: protein-coding

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

BRMS1 transcriptional repressor and anoikis regulator

Symbol: BRMS1
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:66,337,332-66,345,136
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 32260
genomic end: 66345125
exact match: identifiers.org/ncbigene/25855
genomic start: 66104804
cytogenetic location: 11q13.2

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Breast cancer metastasis suppressor 1 is a protein that in humans is encoded by the BRMS1 gene.

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus, and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.