Research
13 papers- Recent Advancement in Synthesis and Bioactivities of 1,3,4-Oxadiazole.Current organic synthesis · 2023
- Effects of butalamine on oxydative phosphorylations in the rat liver.Arzneimittel-Forschung · 1976
- [Clinical trial of butalamine].Revue de laryngologie - otologie - rhinologie · 1973
- [Butalamine hydrochloride. A new vasoactive substance].Fortschritte der Medizin · 1976
- [Conservative therapy of arterial occlusive diseases. Double-blind study on the effect of butalamine hydrochloride].Fortschritte der Medizin · 1980
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 316.226
Show 4 more facts
- chemical formula
- C₁₈H₂₈N₄O
- canonical SMILES
- CCCCN(CCCC)CCNC1=NC(=NO1)C2=CC=CC=C2
- isomeric SMILES
- CCCCN(CCCC)CC/N=C\1/N=C(NO1)C2=CC=CC=C2
- subject has role
- vasodilator agent
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Butalamine is a vasodilator.
==Synthesis== The reaction of benzamidoxime (1) with chlorine and subsequent reaction with cyanamide (3) gives 5-amino-3-phenyl-1,2,4-oxadiazole (4). Base catalyzed alkylation with dibutylaminoethyl chloride (5) completes the synthesis of butalamine (6). thumb|left|501px|Synthesis of butalamine
Excerpted from Wikipedia’s “butalamine” article, available under the CC BY-SA 4.0 licence.