CA12

Also known as CAXII, HsT18816, CA-XII, T18816, carbonic anhydrase 12

protein-coding gene in the species Homo sapiens

Gene data

CA12

Name: carbonic anhydrase 12
Type: protein-coding
Aliases: CA-XII, CAXII, HsT18816, T18816

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014].

via MyGene.info