CALU
Sign in to saveAlso known as calumenin
Calumenin is a protein that in humans is encoded by the CALU gene.
In the Vinony graph
Within Vinony's link graph, CALU is referenced by 5 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It sits within the topics EF-hand-containing proteins and Genes on human chromosome 7.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CALU- Name
- calumenin
- Type
- protein-coding
- Position
- 128,739,292–128,773,400 (+)
- Ensembl
- ENSG00000128595
- RefSeq RNA
- NM_001130674.3, NM_001199671.2, NM_001199672.2, NM_001199673.2, NM_001199674.1
- RefSeq protein
- NP_001124146.1, NP_001186600.1, NP_001186601.1, NP_001186602.1, NP_001210.1
The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
calumenin
- Symbol
- CALU
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:128,739,292-128,773,400
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 936
- chromosome
- human chromosome 7
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/813
- genomic end
- 128773400
- genomic start
- 128379346
- cytogenetic location
- 7q32.1
- expressed in
- popliteal artery
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Calumenin is a protein that in humans is encoded by the CALU gene.
Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (RCN2), and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.
Excerpted from Wikipedia’s “CALU” article, available under the CC BY-SA 4.0 licence.