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GeneQ17854152· pop 5· linked from 122 articles

Also known as ADNIV, HTRA3, VRNI, nCL-3, calpain 5

Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.

Gene data

CAPN5
Name
calpain 5
Type
protein-coding
Aliases
ADNIV, HTRA3, VRNI, nCL-3

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

calpain 5

Symbol
CAPN5
Biotype
Protein coding
Organism
Homo sapiens
Location
11:77,066,961-77,126,155
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
31212
genomic start
77066961
genomic end
76837201
cytogenetic location
11q13.5
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via Wikidata · CC0

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Calpain-5 is a protein that in humans is encoded by the CAPN5 gene.

Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.

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