CAPN2

Name

calpain 2

Type

protein-coding

Position

223,701,593–223,776,018 (+)

Aliases

CANP2, CANPL2, CANPml, mCANP

Ensembl

ENSG00000162909

RefSeq RNA

NM_001146068.2, NM_001748.5, XM_047431344.1, XM_054338935.1

RefSeq protein

NP_001139540.1, NP_001739.3, XP_047287300.1, XP_054194910.1

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

via MyGene.info

Gene · Ensembl

calpain 2

Symbol

CAPN2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:223,701,561-223,776,018

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein CAPN2 PDB 1df0.png

via Wikidata · CC0