cefiderocol

Also known as S-649266

Cefiderocol, sold under the brand name Fetroja (by Shionogi) among others, is an antibiotic used to treat complicated urinary tract infections when no other options are available. It is indicated for the treatment of multi-drug-resistant Gram-negative bacteria including Pseudomonas aeruginosa. It is given by injection into a vein.

Key facts

Drug.image: Cefiderocol skeletal formula labelled.svg
Drug.image_class: skin-invert-image
Drug.width: 300
Drug.image2: Cefiderocol_ball-and-stick_model.png
Drug.image_class2: bg-transparent
Drug.width2: 275
Drug.tradename: Fetroja, Fetcroja
Drug.MedlinePlus: a620008
Drug.licence_EU: yes
Drug.DailyMedID: Cefiderocol_sulfate_tosylate
Drug.routes_of_administration: Intravenous infusion
Drug.class: Siderophore cephalosporins
Drug.ATC_prefix: J01
Drug.ATC_suffix: DI04
Drug.legal_US: Rx-only
Drug.legal_EU: Rx-only
Drug.legal_status: Rx-only
Drug.protein_bound: 56–58%

via Wikipedia infobox

Research

1,383 papers

via PubMed

Wikidata facts

Mass: 751.15

Show 4 more facts

canonical SMILES: CC(C)(C(=O)O)ON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)C[N+]4(CCCC4)CCNC(=O)C5=C(C(=C(C=C5)O)O)Cl)C(=O)[O-]
chemical formula: C₃₀H₃₄ClN₇O₁₀S₂
isomeric SMILES: CC(C)(C(=O)O)O/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4(CCCC4)CCNC(=O)C5=C(C(=C(C=C5)O)O)Cl)C(=O)[O-]
Commons category: Cefiderocol

Sources (2)

via Wikidata · CC0

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