سفیدروکل

Key facts

Drug.image

Cefiderocol skeletal formula labelled.svg

Drug.image_class

skin-invert-image

Drug.width

300

Drug.image2

Cefiderocol_ball-and-stick_model.png

Drug.image_class2

bg-transparent

Drug.width2

275

Drug.tradename

Fetroja, Fetcroja

Drug.MedlinePlus

a620008

Drug.licence_EU

yes

Drug.DailyMedID

Cefiderocol_sulfate_tosylate

Drug.routes_of_administration

Intravenous infusion

Drug.class

Siderophore cephalosporins

Drug.ATC_prefix

J01

Drug.ATC_suffix

DI04

Drug.legal_US

Rx-only

Drug.legal_EU

Rx-only

Drug.legal_status

Rx-only

Drug.protein_bound

56–58%

via Wikipedia infobox

Chemical data

Formula

C30H34ClN7O10S2

Molecular weight

752.2 g/mol

IUPAC name

(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-3-[[1-[2-[(2-chloro-3,4-dihydroxybenzoyl)amino]ethyl]pyrrolidin-1-ium-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

SMILES

CC(C)(C(=O)O)O/N=C(\C1=CSC(=N1)N)/C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4(CCCC4)CCNC(=O)C5=C(C(=C(C=C5)O)O)Cl)C(=O)[O-]

InChIKey

DBPPRLRVDVJOCL-FQRUVTKNSA-N

XLogP

1

Polar surface area

310 Ų

H-bond donors

6

H-bond acceptors

15

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

2019

Admin. routes

parenteral

Indications

infection, urinary tract infection, pneumonia, bacterial pneumonia

via ChEMBL · EBI

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

751.15

via Wikidata · CC0