CENPK
Sign in to saveAlso known as AF5alpha, CENP-K, P33, Solt, FKSG14, centromere protein K
Centromere protein K is a protein that in humans is encoded by the CENPK gene.
Gene data
CENPK- Name
- centromere protein K
- Type
- protein-coding
- Position
- 65,517,765–65,563,552 (−)
- Aliases
- AF5alpha, CENP-K, FKSG14, P33, Solt
- Ensembl
- ENSG00000123219
- RefSeq RNA
- NM_001267038.2, NM_001349367.2, NM_001349368.2, NM_001349369.2, NM_022145.5
- RefSeq protein
- NP_001253967.1, NP_001336296.1, NP_001336297.1, NP_001336298.1, NP_071428.2
CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Amplification of signal from the kinetochoresAmplification of signal from unattached kinetochores via a MAD2 inhibitory signalSignal TransductionCell CycleSignaling by Rho GTPasesRHO GTPase EffectorsSeparation of Sister ChromatidsResolution of Sister Chromatid CohesionMitotic Metaphase and AnaphaseRHO GTPases Activate Formins
via MyGene.info
Gene · Ensembl
centromere protein K
- Symbol
- CENPK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:65,517,765-65,563,552
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11035
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64105
- genomic end
- 65563168
- genomic start
- 64813593
- chromosome
- human chromosome 5
- cytogenetic location
- 5q12.3
- expressed in
- bone marrow
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Centromere protein K is a protein that in humans is encoded by the CENPK gene.
== Interactions ==
Excerpted from Wikipedia’s “CENPK” article, available under the CC BY-SA 4.0 licence.