CEP350

Also known as CAP350, GM133, centrosomal protein 350

Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.

Gene data

CEP350

Name: centrosomal protein 350
Type: protein-coding
Aliases: CAP350, GM133

The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

centrosomal protein 350

Symbol: CEP350
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:179,954,674-180,114,880
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein CEP350 PDB 2coz.png

Show 5 more facts

HomoloGene ID: 8879
exact match: identifiers.org/ncbigene/9857
genomic end: 180114875
genomic start: 179954773
cytogenetic location: 1q25.2

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Centrosome-associated protein 350 is a protein that in humans is encoded by the CEP350 gene.

CEP350 is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated proteins. It primarily localizes to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. CEP350 is required to anchor microtubules at the centrosome. Furthermore, it increases the stability of growing centrioles.