PIBF1

Also known as PIBF, C13orf24, CEP90, progesterone immunomodulatory binding factor 1, JBTS33

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has also been named CEP90.

Gene data

PIBF1

Name: progesterone immunomodulatory binding factor 1
Type: protein-coding
Position: 72,781,641–73,017,823 (+)
Aliases: C13orf24, CEP90, JBTS33, PIBF
Ensembl: ENSG00000083535
RefSeq RNA: NM_001349655.2, NM_006346.4, NR_146205.2, NR_146206.2, XM_011534882.4
RefSeq protein: NP_001336584.1, NP_006337.2, XP_011533184.1, XP_011533186.1, XP_011533187.1

This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017].

Gene Ontology

Biological process

mitotic metaphase chromosome alignment

Article

3 sections

Contents

References
External links
Further reading

Progesterone-induced-blocking factor 1 is a protein that in humans is encoded by the PIBF1 gene. It has been shown to localize to the centrosome and has also been named CEP90.

==References==