CGAS

Also known as C6orf150, h-cGAS, Mab-21 domain containing 1, MB21D1, cyclic GMP-AMP synthase, Cyclic GMP-AMP synthase

Cyclic GMP-AMP synthase is a protein that in humans is encoded by the CGAS gene. It's an enzyme, a nucleotidyltransferase, a cyclic GMP-AMP synthase. == References ==

Gene data

CGAS

Name: cyclic GMP-AMP synthase
Type: protein-coding
Position: 73,413,515–73,461,726 (−)
Aliases: C6orf150, D4, MB21D1, h-cGAS
Ensembl: ENSG00000164430
RefSeq RNA: NM_001410911.1, NM_138441.3
RefSeq protein: NP_001397840.1, NP_612450.2

Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; chromatin binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including cellular response to exogenous dsRNA; positive regulation of intracellular signal transduction; and regulation of defense response. Located in several cellular components, including cytosol; nucleus; and site of double-strand break. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

activation of innate immune response activation of innate immune response

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Article

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References
Further reading
External links

Cyclic GMP-AMP synthase is a protein that in humans is encoded by the CGAS gene. It's an enzyme, a nucleotidyltransferase, a cyclic GMP-AMP synthase. == References ==

== Further reading ==