GTPase
Sign in to saveGTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). The GTP binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases.
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- Commons category
- Guanosine triphosphatase
- EC enzyme number
- 3.6.1.15
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~11 min read
Article
15 sectionsContents
- Functions
- Mechanism
- G domain GTPases
- TRAFAC class
- Translation factor superfamily{{anchor|Translation factor family}}
- Heterotrimeric G proteins
- Small GTPases
- Myosin-kinesin superfamily
- Large GTPases
- SIMIBI class
- Translocation factors
- Other GTPases
- See also
- References
- External links
GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). The GTP binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases.
==Functions== GTPases function as molecular switches or timers in many fundamental cellular processes.
Connections
phosphates
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translation
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G protein-coupled recepteishon
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ras subfamily
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protein targeting
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translation elongation factor
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RAN
Gene
GTPase-activating proteins
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ADP ribosylation factor
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cell
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protein
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magnesium
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enzyme
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ion
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taste
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digital object identifier
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visual perception
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ribosome
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sense of smell
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plasma membrane
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