GTPase
Sign in to saveGTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). The GTP binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases.
In the Vinony graph
Within Vinony's link graph, GTPase is referenced by 494 other articles, and connects out to phosphates, translation and G protein-coupled recepteishon.
Vinony files it under EC 3.6.5 and Signal transduction.
Its subject is documented across 17 Wikipedia language editions.
Wikidata facts
- Subclass of
- nucleoside-triphosphatase
Show 2 more facts
- Commons category
- Guanosine triphosphatase
- EC enzyme number
- 3.6.1.15
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
15 sectionsContents
- Functions
- Mechanism
- G domain GTPases
- TRAFAC class
- Translation factor superfamily{{anchor|Translation factor family}}
- Heterotrimeric G proteins
- Small GTPases
- Myosin-kinesin superfamily
- Large GTPases
- SIMIBI class
- Translocation factors
- Other GTPases
- See also
- References
- External links
GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP). The GTP binding and hydrolysis takes place in the highly conserved P-loop "G domain", a protein domain common to many GTPases.
==Functions== GTPases function as molecular switches or timers in many fundamental cellular processes.
Excerpted from Wikipedia’s “GTPase” article, available under the CC BY-SA 4.0 licence.