CHN2

Name

chimerin 2

Type

protein-coding

Position

29,146,547–29,514,334 (+)

Aliases

ARHGAP3, BCH, CHN2-3, RHOGAP3

Ensembl

ENSG00000106069

RefSeq RNA

NM_001039936.3, NM_001293069.1, NM_001293070.2, NM_001293071.2, NM_001293072.2

RefSeq protein

NP_001035025.1, NP_001279999.1, NP_001280000.1, NP_001280001.1, NP_001280002.1

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014].

via MyGene.info

Gene · Ensembl

chimerin 2

Symbol

CHN2

Biotype

Protein coding

Organism

Homo sapiens

Location

7:29,146,547-29,514,334

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein CHN2 PDB 1xa6.png

via Wikidata · CC0