FGD2
Sign in to saveAlso known as ZFYVE4, FYVE, RhoGEF and PH domain containing 2
FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene.
Gene data
FGD2- Name
- FYVE, RhoGEF and PH domain containing 2
- Type
- protein-coding
- Position
- 37,005,645–37,029,299 (+)
- Aliases
- ZFYVE4
- Ensembl
- ENSG00000146192
- RefSeq RNA
- NM_173558.4, XM_011514372.3, XM_011514373.3, XM_047418332.1, XM_047418333.1
- RefSeq protein
- NP_775829.2, XP_011512674.1, XP_011512675.1, XP_047274288.1, XP_047274289.1
The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
FYVE, RhoGEF and PH domain containing 2
- Symbol
- FGD2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:37,005,637-37,030,923
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8438
- exact match
- identifiers.org/ncbigene/221472
- genomic end
- 37029069
- genomic start
- 36973422
- cytogenetic location
- 6p21.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- See also
- References
- Further reading
FYVE, RhoGEF and PH domain-containing protein 2 (FGD2), also known as zinc finger FYVE domain-containing protein 4 (ZFYVE4), is a protein that in humans is encoded by the FGD2 gene.
It is a member of the FYVE, RhoGEF and PH domain containing family.
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via Wikidata sitelinks · CC0