Structure via PubChem · Public domain (PubChem)
chrysin
Sign in to saveAlso known as NSC-407436, 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one, 5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one, 5,7-dihydroxy-2-phenylchromen-4-one
Chrysin, also called 5,7-dihydroxyflavone, is a flavone found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum. It is extracted from various plants, such as the blue passion flower (Passiflora caerulea). Following oral intake by humans, chrysin has low bioavailability and rapid excretion. It is under basic research to evaluate its safety and potential biological effects.
Chemical data
- Formula
- C15H10O4
- Molecular weight
- 254.24 g/mol
- IUPAC name
- 5,7-dihydroxy-2-phenylchromen-4-one
- SMILES
- C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
- InChIKey
- RTIXKCRFFJGDFG-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 66.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
Show 7 more facts
- found in taxon
- broad bean
- chemical formula
- C₁₅H₁₀O₄
- Commons category
- Chrysin
- canonical SMILES
- C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
- melting point
- 287
- has characteristic
- bitterness
- subject has role
- aromatase inhibitors
via Wikidata · CC0
~4 min read
Encyclopedic overview
7 sectionsContents
- Occurrence
- Bioavailability
- Oral and topical application
- Safety
- Research
- Bibliography
- References
Chrysin, also called 5,7-dihydroxyflavone, is a flavone found in honey, propolis, the passion flowers, Passiflora caerulea and Passiflora incarnata, and in Oroxylum indicum. It is extracted from various plants, such as the blue passion flower (Passiflora caerulea). Following oral intake by humans, chrysin has low bioavailability and rapid excretion. It is under basic research to evaluate its safety and potential biological effects.
Chrysin is an ingredient in dietary supplements. As of 2016, there was no clinical use of chrysin, and no evidence for its effect on testosterone levels. In 2016, the US Food and Drug Administration did not recommend chrysin be included on the list of bulk drug substances that can be used in compounding under section 503A of the Federal Food, Drug, and Cosmetic Act.
Excerpted from Wikipedia’s “chrysin” article, available under the CC BY-SA 4.0 licence.