Structure via PubChem · Public domain (PubChem)
ciclesonide
Sign in to saveAlso known as RPR-251526, (R)-11b,16a,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde 21-isobutyrate
Ciclesonide, sold under the brand name Omnaris among others, is a glucocorticoid used to treat asthma and allergic rhinitis.
Chemical data
- Formula
- C32H44O7
- Molecular weight
- 540.7 g/mol
- IUPAC name
- [2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 2-methylpropanoate
- SMILES
- CC(C)C(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)C=C[C@]45C)O)C)O[C@H](O2)C6CCCCC6
- InChIKey
- LUKZNWIVRBCLON-GXOBDPJESA-N
- XLogP
- 5.3
- Polar surface area
- 99.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2006
- Admin. routes
- topical
- Indications
- allergic rhinitis, seasonal allergic rhinitis, Airway obstruction, Nasal congestion
via ChEMBL · EBI
Research
518 papers- Ciclesonide.2006
- Inhaled ciclesonide for outpatients with COVID-19: A meta-analysis.Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi · 2022
- Ciclesonide.Drugs · 2004
- Ciclesonide nasal spray: in allergic rhinitis.Drugs · 2008
- Ciclesonide: a novel inhaled corticosteroid.Expert opinion on investigational drugs · 2004
via PubMed
Wikidata facts
- Has part
- carbon
- Mass
- 540.309
- Has use
- medication
Show 6 more facts
- World Health Organisation international non-proprietary name
- ciklesonid
- chemical formula
- C₃₂H₄₄O₇
- defined daily dose
- 0.2
- canonical SMILES
- CC(C)C(=O)OCC(=O)C12C(CC3C1(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)OC(O2)C6CCCCC6
- isomeric SMILES
- CC(C)C(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@H]4[C@H]3CCC5=CC(=O)C=C[C@]45C)O)C)O[C@H](O2)C6CCCCC6
- Commons category
- Ciclesonide
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Society and culture
- Brand names
- References
- Further reading
Ciclesonide, sold under the brand name Omnaris among others, is a glucocorticoid used to treat asthma and allergic rhinitis.
Side effects of the medication include headache, nosebleeds, and inflammation of the nose and throat linings.
Excerpted from Wikipedia’s “ciclesonide” article, available under the CC BY-SA 4.0 licence.