CLDN1
Sign in to saveAlso known as CLD1, ILVASC, SEMP1, claudin 1
Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins.
Gene data
CLDN1- Name
- claudin 1
- Type
- protein-coding
- Position
- 190,305,707–190,322,446 (−)
- Aliases
- CLD1, ILVASC, SEMP1
- Ensembl
- ENSG00000163347
- RefSeq RNA
- NM_021101.5
- RefSeq protein
- NP_066924.1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 1
- Symbol
- CLDN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:190,305,706-190,322,977
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9620
- exact match
- identifiers.org/ncbigene/9076
- genomic end
- 190322446
- genomic start
- 190305707
- cytogenetic location
- 3q28
Sources (3)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins.
== Function ==