CLCA1
Sign in to saveAlso known as CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1, chloride channel accessory 1
Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.
Gene data
CLCA1- Name
- chloride channel accessory 1
- Type
- protein-coding
- Aliases
- CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
chloride channel accessory 1
- Symbol
- CLCA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:86,468,368-86,501,401
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 984
- genomic start
- 86468368
- exact match
- identifiers.org/ncbigene/1179
- genomic end
- 86500259
- cytogenetic location
- 1p22.3
Sources (4)
via Wikidata · CC0
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Article
4 sectionsContents
- See also
- References
- Further reading
- External links
Chloride channel accessory 1 is a protein that in humans is encoded by the CLCA1 gene.
This gene encodes a member of the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same region on chromosome 1p31-p22 and share a high degree of homology in size, sequence, and predicted structure, but differ significantly in their tissue distributions. The encoded protein is expressed as a precursor protein that is processed into two cell-surface-associated subunits, although the site at which the precursor is cleaved has not been precisely determined. The encoded protein may be involved in mediating calcium-activated chloride conductance in the intestine. Protein structure prediction methods suggest the N-terminal region of CLCA1 protein is a zinc metalloprotease.