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Structure via PubChem · Public domain (PubChem)
cloforex
Sign in to saveCloforex (Oberex) is an anorectic of the amphetamine class. It is a prodrug to chlorphentermine. It never became a mass produced drug in part due to the side effects found in mice. Mice who consumed 75 mg of cloforex a day experienced weight loss along with pulmonary hypertension and hair loss.
Chemical data
- Formula
- C13H18ClNO2
- Molecular weight
- 255.74 g/mol
- IUPAC name
- ethyl N-[1-(4-chlorophenyl)-2-methylpropan-2-yl]carbamate
- SMILES
- CCOC(=O)NC(C)(C)CC1=CC=C(C=C1)Cl
- InChIKey
- TZWKUQDQKPYNLL-UHFFFAOYSA-N
- XLogP
- 3.5
- Polar surface area
- 38.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 255.103
Show 3 more facts
- chemical formula
- C₁₃H₁₈ClNO₂
- canonical SMILES
- CCOC(=O)NC(C)(C)CC1=CC=C(C=C1)Cl
- Commons category
- Cloforex
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Cloforex (Oberex) is an anorectic of the amphetamine class. It is a prodrug to chlorphentermine. It never became a mass produced drug in part due to the side effects found in mice. Mice who consumed 75 mg of cloforex a day experienced weight loss along with pulmonary hypertension and hair loss.
==See also== Alaproclate
Excerpted from Wikipedia’s “cloforex” article, available under the CC BY-SA 4.0 licence.