Colony stimulating factor 3
Sign in to saveAlso known as granulocyte colony-stimulating factor, granulocyte-colony stimulating factor, colony stimulating factor 3 (granulocyte), pluripoietin, CSF3
mammalian protein found in Homo sapiens
Protein · UniProt
Granulocyte colony-stimulating factor
- Gene
- CSF3
- Organism
- Homo sapiens (Human)
- Length
- 207 aa
- Molecular mass
- 22,293 Da
- Evidence
- 1: Evidence at protein level
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes
3D-structureAlternative splicingCytokineDirect protein sequencingDisulfide bondGlycoproteinGrowth factorPharmaceutical
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Swiss-Prot (reviewed) · via UniProt
Clinical Trials
392 registered- PHASE2COMPLETEDPegfilgrastim PBPC Mobilization StudyAmgen · NCT00066092
- PHASE3COMPLETEDCombination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With OsteosarcomaEuropean Organisation for Research and Treatment of Cancer - EORTC · NCT00002539
- PHASE2COMPLETEDColony-Stimulating Factors to Relieve Neutropenia in Patients With Recurrent Non-Hodgkin's LymphomaUniversity of Nebraska · NCT00004192
- PHASE2/PHASE3COMPLETEDGranulocyte Colony Stimulating Factor And Growth Hormone In Cirrhosis Of Liver: An Open Label StudyPost Graduate Institute of Medical Education and Research, Chandigarh · NCT02451033
- PHASE2COMPLETEDComparison of Anti HIV Drugs Used Alone or in Combination With Cytosine Arabinoside to Treat Progressive Multifocal Leukoencephalopathy (PML) in HIV-Infected PatientsNational Institute of Allergy and Infectious Diseases (NIAID) · NCT00001048
- PHASE1COMPLETEDGranulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 MutationsM.D. Anderson Cancer Center · NCT00943943