COX17

Name

cytochrome c oxidase copper chaperone COX17

Type

protein-coding

Position

119,654,513–119,677,621 (−)

Ensembl

ENSG00000138495

RefSeq RNA

NM_001382002.1, NM_001382003.1, NM_005694.2, NR_167771.1, NR_167772.1

RefSeq protein

NP_001368931.1, NP_001368932.1, NP_005685.1

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

cytochrome c oxidase copper chaperone COX17

Symbol

COX17

Biotype

Protein coding

Organism

Homo sapiens

Location

3:119,654,513-119,677,621

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein COX17 PDB 2RN9.png

via Wikidata · CC0