DMAC2
Sign in to saveAlso known as ATP5SL, ATP5S like, distal membrane arm assembly complex 2, distal membrane arm assembly component 2
ATP synthase subunit s-like protein is a protein that in humans is encoded by the DMAC2 gene. It has a role in the assembly of the distal portion of the Mitochondiral Respiratory Complex 1 (NADH: ubiquinone oxidoreductase) membrane arm. Complex 1 is the largest respiratory complex of the mitochondrial electron transport chain. == Gene == ATP5SL’s preferred name is DMAC2, Distal membrane arm assembly complex 2. DMAC2 is on the minus strand of Chromosome 19 and spans 9400 base pairs. == mRNA == There are 6 exons within ATP5SL's mRNA sequence and 12 known transcript variants that span between 148
In the Vinony graph
Vinony's link graph records 2 inbound references to DMAC2, and connects out to PubMed, Ensembl genome database project and sequence homology.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 6 Wikipedia language editions.
Gene data
DMAC2- Name
- distal membrane arm assembly component 2
- Type
- protein-coding
- Aliases
- ATP5SL
Involved in mitochondrial respiratory chain complex I assembly. Colocalizes with mitochondrial respiratory chain complex I. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
distal membrane arm assembly component 2
- Symbol
- DMAC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:41,431,317-41,440,717
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 9973
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55101
- chromosome
- human chromosome 19
- genomic start
- 41937223
- genomic end
- 41946622
- cytogenetic location
- 19q13.2
Sources (3)
via Wikidata · CC0
~10 min read
Encyclopedic overview
16 sectionsContents
- Gene
- mRNA
- Expression
- Protein
- Amino Acid Composition
- Regions
- Post-translational modification
- Protein Structure
- Protein Interactions
- Conceptual translation
- Homology
- Clinical Significance
- SNPs
- References
- External links
- Further reading
ATP synthase subunit s-like protein is a protein that in humans is encoded by the DMAC2 gene. It has a role in the assembly of the distal portion of the Mitochondiral Respiratory Complex 1 (NADH: ubiquinone oxidoreductase) membrane arm. Complex 1 is the largest respiratory complex of the mitochondrial electron transport chain. == Gene == ATP5SL’s preferred name is DMAC2, Distal membrane arm assembly complex 2. DMAC2 is on the minus strand of Chromosome 19 and spans 9400 base pairs. == mRNA == There are 6 exons within ATP5SL's mRNA sequence and 12 known transcript variants that span between 1489 and 2515 nucleotides.
The 3' untranslated region sequence has 8 large stem loops with 3 overlapping miRNA target binding sites: hsa-miR-4731-5p, hsa-miR-671-5p, and hsa-miR-4786-3p. This site is almost fully conserved in primates; it differs by one base pair. A secondary site of hsa-miR-4731-5p is fully conserved among Primates.
Excerpted from Wikipedia’s “DMAC2” article, available under the CC BY-SA 4.0 licence.