DNA replication factor A complex
Sign in to saveAlso known as GO:0005662, RPA, replication protein A, Replication protein A
conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism
Research
963 papers- Regulated eukaryotic DNA replication origin firing with purified proteins.Nature · 2015
- Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.Cell · 2023
- Replication protein A complex in Thermococcus kodakarensis interacts with DNA polymerases and helps their effective strand synthesis.Bioscience, biotechnology, and biochemistry · 2019
- The human primosome requires replication protein A when copying DNA with inverted repeats.Nucleic acids research · 2025
- Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis.PloS one · 2016
via PubMed
Wikidata facts
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- exact match
- purl.obolibrary.org/obo/GO_0005662
- Commons category
- Replication protein A, repA
Sources (1)
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Connections
DNA replication
Entity
DNA polymerase
Entity
origin of replication
Entity
cryptochrome
Entity
nucleotide-excision repair
Entity
RPA2
Gene
RPA1
Gene
deoxyribonucleic acid
Entity
protein
Entity
eukaryote
Entity
digital object identifier
Entity
mutation
Entity
meiosis
Entity
Q180686
Entity
Saccharomyces cerevisiae
Entity
stoichiometry
Entity
Q229883
Entity
telomere
Entity
DNA repair
Entity
in vitro experiment
Entity