Structure via PubChem · Public domain (PubChem)
eprobemide
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Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol). It is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.
In the Vinony graph
Within Vinony's link graph, eprobemide is referenced by 451 other articles, and connects out to L-tyrosine, monoamine oxidase inhibitor and tetracyclic antidepressant.
Vinony files it under 4-Chlorophenyl compounds, 4-Morpholinyl compounds and Antidepressants.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C14H19ClN2O2
- Molecular weight
- 282.76 g/mol
- IUPAC name
- 4-chloro-N-(3-morpholin-4-ylpropyl)benzamide
- SMILES
- C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
- InChIKey
- YYFGRAGNYHYWEZ-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 282.114
Show 3 more facts
- Commons category
- Eprobemide
- chemical formula
- C₁₄H₁₉ClN₂O₂
- canonical SMILES
- C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Eprobemide (INN) is a pharmaceutical drug that was used as an antidepressant in Russia (under the brand name Бефол/Befol). It is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. Eprobemide differs from moclobemide only in the linker that connects the morpholine fragment with the chlorobenzamide — moclobemide has two carbon atoms while eprobemide has three. Its registration was cancelled on December 30, 2003.
== See also == List of Russian drugs
Excerpted from Wikipedia’s “eprobemide” article, available under the CC BY-SA 4.0 licence.