hepzidine
Sign in to saveHepzidine (INN) is a tricyclic antidepressant which was never marketed. It was first described by 1966. ==Synthesis== The synthesis has been described in the chemical literature: 700px|center| The reduction of dibenzosuberone (1) gives dibenzosuberol [1210-34-0] (2). This alcohol forms ethers exceedingly easily, probably via the carbonium ion. Treatment with N-methyl-4-piperidinol [106-52-5] (3) in the presence of acid gives hepzidine (4).
Wikidata facts
- Mass
- 307.194
Show 3 more facts
- chemical formula
- C₂₁H₂₅NO
- canonical SMILES
- CN1CCC(CC1)OC2C3=CC=CC=C3CCC4=CC=CC=C24
- Commons category
- Hepzidine
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- Synthesis
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Hepzidine (INN) is a tricyclic antidepressant which was never marketed. It was first described by 1966. ==Synthesis== The synthesis has been described in the chemical literature: 700px|center| The reduction of dibenzosuberone (1) gives dibenzosuberol [1210-34-0] (2). This alcohol forms ethers exceedingly easily, probably via the carbonium ion. Treatment with N-methyl-4-piperidinol [106-52-5] (3) in the presence of acid gives hepzidine (4).
==See also== Diphenylpyraline is selfsame but is based on a benzhydrol aromatic pharmacophore. Dibenzosuberol is also used in the synthesis of Deptramine (DPH analog) as well as Oxitriptyline & Deptropine.