EXTL2
Sign in to saveAlso known as EXTR2, exostosin-like glycosyltransferase 2, exostosin like glycosyltransferase 2
Exostosin-like 2 is a protein that in humans is encoded by the EXTL2 gene. EXTL2 Glycosyltransferase is required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. (https://www.phosphosite.org/overviewExecuteAction?id=5020882)
In the Vinony graph
Vinony's link graph records 3 inbound references to EXTL2, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 7 Wikipedia language editions.
Gene data
EXTL2- Name
- exostosin like glycosyltransferase 2
- Type
- protein-coding
- Aliases
- EXTR2
Enables alpha-1,4-N-acetylgalactosaminyltransferase activity and glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Located in cytosol; endoplasmic reticulum; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
exostosin like glycosyltransferase 2
- Symbol
- EXTL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:100,871,371-100,896,000
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 1102
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2135
- genomic end
- 100895179
- genomic start
- 101337943
- chromosome
- human chromosome 1
- cytogenetic location
- 1p21.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Exostosin-like 2 is a protein that in humans is encoded by the EXTL2 gene. EXTL2 Glycosyltransferase is required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. (https://www.phosphosite.org/overviewExecuteAction?id=5020882)
==References==
Excerpted from Wikipedia’s “EXTL2” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0